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Formaldehyde in Cosmetics


  Detailled application note formaldehyde (pdf)

Free formaldehyde is used for long-term stabilization in cosmetic products.
The potential cancerogenity demands effective and reliable analysis.

The quantitative determination of free formaldehyde often is problematic. The detection characteristics are very unfavorable. Consequently, derivatization is necessary to achieve the required sensitivity.

According to method K84.00-7(EG) chromatographic separation by HPLC column is followed by derivatization. This does not influence the equilibrium between donator and free formaldehyde. A UV/VIS or fluorescence detector is used for detection.

LCTech offers the  complete post-column derivatization system PINNACLE PCX  for the detection of traces of formaldehyde.   

The certain extra: Within minutes you can rebuild your PINNACLE PCX post column derivatization system for  NDELA analysis.

 Formaldehyde chromatogram
Chromatogram of a shampoo sample, spiked with 0.05% formaldehyde, determination following K84.00-7(EG)

The result is a peak for free
formaldehyde without interferants.